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Ankylosing Spondylitis
 
 
DEFINITION
Ankylosing spondylitis (AS) is a chronic inflammatory disease that primarily affects the sacroiliac joints (where the spine attaches to the pelvis), spine, and hip joints. Ankylosing is a term meaning stiff or rigid and spondylitis means inflammation of the spine. Ankylosing spondylitis most often develops in young adult men and it lasts a lifetime. Early diagnosis and proper treatment can help control the pain and stiffness associated with AS, and may reduce or prevent deformity.
 
 
CAUSES
Although the cause of ankylosing spondylitis (AS) is not known, there is a strong link to a specific genetic marker. Studies show that 90 percent of people with AS are positive for this genetic marker; however, fewer than five percent of these people ever develop AS or a related disease.
 
 
SYMPTOMS
Pain in the low back and buttocks are usually the first symptoms of AS. Progressive stiffening of the spine is usual, with ankylosis (fusion of some or all spinal joints) occurring after some years of disease in many, but not all, patients. A majority of patients have mild or moderate disease with intermittent exacerbations and remissions and maintain some mobility and independence throughout life. In addition to these, one might feel unable to touch their fingers to the floor by a considerable distance, have rigidity of the chest wall reducing the ability to take a deep breath, and have decreased ability to extend and rotate the neck.
 
 
HOW WE CAN HELP
At Accurate Clinical Research we are enrolling AS patients into various clinical programs in search for a new treatment. If you are looking for other options or want to help future generations, today is the perfect day to volunteer. Enroll today for tomorrow’s future.
 
 
OTHER LINKS
http://www.spondylitis.org          • www.arthritis.org
 
 
 
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